Personalised Cancer Plan
Make treatment decisions with greater confidence
Precision insights that complement standard oncology care to guide next-step planning and ongoing monitoring.
Precision-guided personalised plans have been studied across multiple published settings — including associations with tumour response, time without progression, and outcomes in certain high-risk or hard-to-treat cancers.
Personalised Cancer
Care May Influence
Outcomes
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2. Sources: Von Hoff et al., 2010; Tsimberidou et al., 2014; Mosse et al., 2020.
Studies in advanced and pediatric cancers evaluating matched (biomarker-guided) versus non-matched approaches.
Key Studies and What They Are About
Tsimberidou et al.
About: Personalized medicine outcomes in patients with advanced cancer treated in the MD Anderson phase I program.
Findings: Matched treatment approaches were reported alongside differences in clinical outcomes in this cohort.
Von Hoff et al.
About: Molecular profiling used to help select therapy in previously treated metastatic cancer.
Findings: Tumour profiling was explored as a way to support treatment selection in selected refractory cases.
Alix-Panabières & Pantel
About: Clinical relevance of circulating tumor cells and circulating tumor DNA.
Findings: Liquid biopsy approaches may provide additional information for tumour characterization and disease monitoring.
Herzog et al.
About: ChemoID-guided therapy in platinum-resistant ovarian cancer.
Findings: Therapy guidance based on tumour-related testing was evaluated as a potential aid in treatment planning for resistant disease.
Lindeman et al.
About: Updated molecular testing guideline for lung cancer.
Findings: Molecular testing was positioned as an important component of treatment decision-making in appropriate lung cancer settings.
Ross et al.
About: Comprehensive genomic profiling in lung cancer.
Findings: Genomic profiling identified biologically relevant alterations that may help inform further clinical evaluation.
MD Anderson Cancer Center
About: IMPACT study and precision medicine program outcomes in advanced cancer.
Findings: Institutional program data described how molecular matching was being explored within advanced cancer care pathways.
MD Anderson Cancer Center
About: Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT).
Findings: The program framework highlighted the use of molecular profiling to support more individualized oncology assessment.
UC San Diego Moores Cancer Center
About: Molecular profiling and clinical outcomes.
Findings: The study explored potential relationships between tumour profiling and clinical outcome patterns.
UC San Diego Moores Cancer Center
About: Molecular tumor board real-world data in breast and gynecologic cancers.
Findings: Real-world tumour board data may offer added insight into how profiling information is discussed in clinical practice.
National Cancer Institute
About: Molecular Analysis for Therapy Choice in pediatric cancer.
Findings: The trial evaluated whether molecular findings could help guide therapy selection in pediatric oncology.
Precision oncology survival outcomes
About: Survival outcomes in late-stage cancer patients.
Findings: The report summarized outcome differences observed in selected late-stage precision oncology settings.
Precision medicine in lung cancer
About: Clinical benefit analysis in lung cancer.
Findings: The summary described how precision-based approaches may contribute additional context in lung cancer management.
Impact of precision medicine on clinical outcomes
About: How precision medicine may influence clinical outcomes.
Findings: The report outlined observed outcome patterns associated with the use of additional biological information in care planning.
Key Studies and What They Are About
A visual overview of the studies, reports, and institutional references related to precision oncology, molecular profiling, circulating tumor biology, and matched treatment approaches.
Tsimberidou et al.
Journal of Clinical Oncology
About: Personalized medicine outcomes in patients with advanced cancer treated in the MD Anderson phase I program.
Von Hoff et al.
Journal of Clinical Oncology
About: Molecular profiling used to help select therapy in previously treated metastatic cancer.
Alix-Panabières & Pantel
Nature Reviews Clinical Oncology
About: Clinical relevance of circulating tumor cells and circulating tumor DNA.
Herzog et al.
Gynecologic Oncology
About: ChemoID-guided therapy in platinum-resistant ovarian cancer.
Lindeman et al.
Journal of Thoracic Oncology
About: Updated molecular testing guideline for lung cancer.
Ross et al.
Cancer
About: Comprehensive genomic profiling in lung cancer.
MD Anderson Cancer Center
Program overview
About: IMPACT study and precision medicine program outcomes in advanced cancer.
MD Anderson Cancer Center
Program reference
About: Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT).
UC San Diego Moores Cancer Center
PREDICT study
About: Molecular profiling and clinical outcomes.
UC San Diego Moores Cancer Center
Institutional real-world data
About: Molecular tumor board real-world data in breast and gynecologic cancers.
National Cancer Institute
Pediatric MATCH trial
About: Molecular Analysis for Therapy Choice in pediatric cancer.
Precision oncology survival outcomes
Summary report
About: Survival outcomes in late-stage cancer patients.
Precision medicine in lung cancer
Summary report
About: Clinical benefit analysis in lung cancer.
Impact of precision medicine on clinical outcomes
Summary report
About: How precision medicine may influence clinical outcomes.
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