Personalised Cancer Plan

Personalised Cancer Plan

Make treatment decisions with greater confidence

Precision insights that complement standard oncology care to support next-step planning, biomarker evaluation, and ongoing monitoring discussions with your healthcare team.

Precision-guided personalised plans have been studied across multiple published settings — including associations with tumour response, time without progression, and outcomes in certain high-risk or hard-to-treat cancers.

Personalised Cancer
Care May Influence
Outcomes

Difficult-to-treat Cancer Cases1,2
Objective Response Rate (%)
0
10
20
30
40
50
22%
50%
Non-matched
approach
Matched
approach
VS
(values observed in a published study population)
High-risk Paediatric Cancers1,2
Patients without Disease Progression at 2 Years (%)
0
10
20
30
40
50
12%
26%
Non-matched
approach
Matched
approach
VS
(values observed in a published study population)
1. Results observed in a published study. Individual outcomes may vary.

2. Sources: Von Hoff et al., 2010; Tsimberidou et al., 2014; Mosse et al., 2020.
Studies in advanced and paediatric cancers evaluating matched (biomarker-guided) versus non-matched approaches.

Key Studies and What They Are About

Selected published studies and institutional references related to precision oncology, molecular profiling, liquid biopsy, and biomarker-guided treatment approaches.

Clinical study
2014

Tsimberidou et al.

Journal of Clinical Oncology

About: Personalized medicine outcomes in patients with advanced cancer treated in the MD Anderson phase I program.

Findings: Matched treatment approaches were reported alongside differences in clinical outcomes in this cohort.

advanced cancer matched therapy precision oncology
Pilot study
2010

Von Hoff et al.

Journal of Clinical Oncology

About: Molecular profiling used to help select therapy in previously treated metastatic cancer.

Findings: Tumour profiling was explored as a way to support treatment selection in selected refractory cases.

metastatic cancer molecular profiling treatment selection
This section is intended as an educational overview of selected published studies and institutional references related to precision oncology. Individual outcomes may vary, and content should not be interpreted as medical advice or treatment claims.

Key Studies and What They Are About

A visual overview of the studies, reports, and institutional references related to precision oncology, molecular profiling, circulating tumor biology, and matched treatment approaches.

13
Total references in this overview
5
Precision oncology / matched treatment references
4
Molecular profiling / tumor testing references
4
Institutional or summary-report references
Clinical study 2014

Tsimberidou et al.

Journal of Clinical Oncology

About: Personalized medicine outcomes in patients with advanced cancer treated in the MD Anderson phase I program.

advanced cancer matched therapy precision oncology
Pilot study 2010

Von Hoff et al.

Journal of Clinical Oncology

About: Molecular profiling used to help select therapy in previously treated metastatic cancer.

metastatic cancer molecular profiling treatment selection
Review article 2016

Alix-Panabières & Pantel

Nature Reviews Clinical Oncology

About: Clinical relevance of circulating tumor cells and circulating tumor DNA.

CTC ctDNA liquid biopsy
Clinical study 2025

Herzog et al.

Gynecologic Oncology

About: ChemoID-guided therapy in platinum-resistant ovarian cancer.

ovarian cancer drug guidance resistant disease
Guideline 2018

Lindeman et al.

Journal of Thoracic Oncology

About: Updated molecular testing guideline for lung cancer.

lung cancer guideline molecular testing
Genomic profiling study 2013

Ross et al.

Cancer

About: Comprehensive genomic profiling in lung cancer.

lung cancer genomics profiling
Institutional report 2017

MD Anderson Cancer Center

Program overview

About: IMPACT study and precision medicine program outcomes in advanced cancer.

IMPACT advanced cancer program outcomes
Institutional program reference 2012

MD Anderson Cancer Center

Program reference

About: Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT).

program framework molecular profiling precision care
Institutional study reference 2016

UC San Diego Moores Cancer Center

PREDICT study

About: Molecular profiling and clinical outcomes.

PREDICT molecular profiling clinical outcomes
Real-world data reference 2022

UC San Diego Moores Cancer Center

Institutional real-world data

About: Molecular tumor board real-world data in breast and gynecologic cancers.

tumor board breast cancer gynecologic cancer
Trial reference 2020

National Cancer Institute

Pediatric MATCH trial

About: Molecular Analysis for Therapy Choice in pediatric cancer.

pediatric cancer MATCH targeted therapy
Clinical study summary report 2025

Precision oncology survival outcomes

Summary report

About: Survival outcomes in late-stage cancer patients.

late-stage cancer survival summary report
Clinical study summary report 2022

Precision medicine in lung cancer

Summary report

About: Clinical benefit analysis in lung cancer.

lung cancer clinical benefit summary report
Clinical study summary report 2021

Impact of precision medicine on clinical outcomes

Summary report

About: How precision medicine may influence clinical outcomes.

clinical outcomes precision medicine summary report
This layout is a visual summary based on the reference list you provided. For publication use, you may want to verify titles, years, journal formatting, and whether some entries are peer-reviewed articles, institutional pages, or internal summary reports.

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