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Discover Personalized Insights for Every Cancer
Learn how different types of cancer are diagnosed, treated, and supported—with care tailored to you.
Malignant Fibrous Histiocytoma (Undifferentiated Pleomorphic Sarcoma)
Malignant fibrous histiocytoma (MFH), now more commonly called undifferentiated pleomorphic sarcoma (UPS), is a high-grade soft tissue sarcoma. It typically arises in the limbs or retroperitoneum of older adults and is known for aggressive behavior.
Intraocular Melanoma (Uveal Melanoma)
Intraocular melanoma is the most common primary eye cancer in adults, originating from melanocytes in the uveal tract (iris, ciliary body, or choroid). It is distinct from skin melanoma but shares similar cellular origins.
Yolk Sac Tumor (Endodermal Sinus Tumor)
Yolk sac tumor (YST), also known as endodermal sinus tumor, is a malignant germ cell tumor that arises from primitive germ cells resembling the yolk sac during embryonic development. It is most common in children and young adults, affecting the testes in males and ovaries in females, though it can also occur in extragonadal sites such as the mediastinum, retroperitoneum, or sacrococcygeal region.
Yolk sac tumors are highly aggressive but often chemosensitive, and modern treatments have significantly improved survival rates.
Ewing Sarcoma
Ewing sarcoma is a rare and aggressive cancer that forms in the bone or soft tissue, most commonly in children and adolescents. It usually affects the pelvis, femur, ribs, and chest wall.
Esophageal Cancer
Esophageal cancer begins in the esophagus, the muscular tube that carries food from the throat to the stomach. It is an aggressive cancer, often diagnosed at a late stage. There are two major types:
• Adenocarcinoma: typically starts in the lower esophagus; associated with Barrett’s esophagus and GERD
• Squamous cell carcinoma: usually found in the upper or middle esophagus; linked to smoking and alcohol use
Astrocytoma
Astrocytoma is a type of brain tumor that originates from astrocytes, the star-shaped glial cells in the brain and spinal cord that support and nourish neurons. Astrocytomas are part of a broader category known as gliomas and are classified based on their grade (I to IV), which reflects how fast the tumor grows and how likely it is to spread.
Grade I (Pilocytic Astrocytoma): Typically benign and slow-growing, often seen in children.
Grade II (Diffuse Astrocytoma): Infiltrative, slow-growing but may progress.
Grade III (Anaplastic Astrocytoma): Malignant, faster-growing.
Grade IV (Glioblastoma): Most aggressive form.
Osteosarcoma
Osteosarcoma is the most common primary bone cancer, usually originating in the long bones (e.g., femur, tibia, humerus). It most commonly affects children, adolescents, and young adults, particularly during growth spurts.
Myeloproliferative Neoplasms (MPNs)
Myeloproliferative neoplasms (MPNs) are a group of chronic blood cancers where the bone marrow makes too many red cells, white cells, or platelets. They are linked to mutations in genes such as JAK2, CALR, and MPL, and may remain stable for years or progress to myelofibrosis or acute leukemia.
The three main types of classic MPNs are:
• Polycythemia vera (PV) – too many red blood cells
• Essential thrombocythemia (ET) – too many platelets
• Primary myelofibrosis (PMF) – scarring of the bone marrow
Secondary Eye Metastases
Secondary eye metastases are cancers that spread to the eye from other primary sites, most commonly the breast, lung, prostate, kidney, and gastrointestinal tract. These are the most frequent intraocular malignancies in adults, typically affecting the choroid.
Personalized Cancer Insights by Category
You’re not alone. Learn more about cancers that affect the same body systems—and explore resources that can help you move forward with clarity.
Bone and Connective Tissue Cancers
Cancers affecting bones, cartilage, muscles, and connective tissues.
Includes brain tumors and cancers of the spinal cord and nerves.
Cancers involving the eye and surrounding orbital tissues.
Female Reproductive System Cancers
Cervical, ovarian, uterine, and other cancers affecting women’s reproductive organs.
Stomach, colon, pancreas, liver, and other digestive system cancers.
Cancers involving the eye and surrounding orbital tissues.
Head, Neck, and Respiratory System
Includes mouth, throat, nasal, and lung cancers.
Leukemia, lymphoma, and blood-related cancers.
Male Reproductive System Cancers
Prostate, testicular, and other cancers affecting men’s reproductive organs.
Cancers most commonly found in children and adolescents.
Uncommon or unclassified cancer types.
Melanoma and cancers of skin, fat, and soft connective tissues.
Understand Precision Testing
Learn how liquid biopsy and chemo sensitivity testing can personalize your treatment plan.
Make Informed Decisions
Gain knowledge to actively participate in treatment discussions with your healthcare team.
Improve Treatment Outcomes
Discover how precision medicine and metabolic therapies can enhance treatment effectiveness.
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