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Precision insights that complement standard oncology care to support next-step planning, biomarker evaluation, and ongoing monitoring discussions with your healthcare team.

Key Studies and Clinical References

Selected studies and institutional references related to precision oncology, molecular profiling, biomarker-guided treatment strategies, liquid biopsy, and tumour-informed clinical decision support.

Clinical Study
2014

Tsimberidou et al.

Journal of Clinical Oncology

About: Personalized medicine outcomes in advanced cancer patients treated within the MD Anderson phase I program.

Findings: Matched treatment approaches were reported alongside differences in clinical outcome patterns in selected patients.

advanced cancer matched therapy precision oncology
Pilot Study
2010

Von Hoff et al.

Journal of Clinical Oncology

About: Molecular profiling used to support therapy selection in metastatic cancer.

Findings: Tumour profiling was explored as a tool to support individualized treatment planning in refractory disease.

metastatic cancer molecular profiling therapy selection
Review Article
2016

Alix-Panabières & Pantel

Nature Reviews Clinical Oncology

About: Clinical relevance of circulating tumour cells and circulating tumour DNA.

Findings: Liquid biopsy technologies may provide additional information for tumour characterization and monitoring.

CTC ctDNA liquid biopsy
Clinical Study
2025

Herzog et al.

Gynecologic Oncology

About: ChemoID-guided therapy in platinum-resistant ovarian cancer.

Findings: Therapy guidance based on tumour-related testing was evaluated as a potential aid in resistant disease management.

ovarian cancer drug guidance resistant disease
Guideline
2018

Lindeman et al.

Journal of Thoracic Oncology

About: Updated molecular testing guideline for lung cancer.

Findings: Molecular testing was highlighted as an important component of treatment decision-making in selected lung cancer settings.

lung cancer guideline molecular testing
Genomic Profiling Study
2013

Ross et al.

Cancer

About: Comprehensive genomic profiling in lung cancer.

Findings: Genomic profiling identified biologically relevant alterations that may support further clinical evaluation.

lung cancer genomics profiling
Institutional Report
2017

MD Anderson Cancer Center

IMPACT Program Overview

About: Institutional precision medicine program outcomes in advanced cancer.

Findings: Program data described how molecular matching strategies were being explored within oncology care pathways.

IMPACT advanced cancer program outcomes
Institutional Reference
2012

MD Anderson Cancer Center

Initiative for Molecular Profiling and Advanced Cancer Therapy

About: Molecular profiling initiative supporting individualized oncology assessment.

Findings: The framework highlighted how tumour profiling could contribute additional information for clinical evaluation.

molecular profiling precision care program framework
Institutional Study
2016

UC San Diego Moores Cancer Center

PREDICT Study

About: Molecular profiling and clinical outcome evaluation.

Findings: The study explored possible relationships between tumour profiling and clinical outcome trends.

PREDICT molecular profiling clinical outcomes
Real-world Data
2022

UC San Diego Moores Cancer Center

Molecular Tumor Board Real-world Data

About: Real-world molecular tumour board data in breast and gynecologic cancers.

Findings: Tumour board discussions may provide additional context regarding the use of profiling information in clinical practice.

tumor board breast cancer gynecologic cancer
Clinical Trial
2020

National Cancer Institute

Pediatric MATCH Trial

About: Molecular Analysis for Therapy Choice in pediatric oncology.

Findings: The trial evaluated whether molecular findings could support targeted therapy selection in pediatric cancer.

pediatric cancer MATCH targeted therapy
Clinical Summary
2025

Precision Oncology Survival Outcomes

Summary Report

About: Survival outcomes in selected late-stage cancer populations.

Findings: Outcome differences were summarized across selected precision oncology settings.

late-stage cancer survival precision oncology
Clinical Summary
2022

Precision Medicine in Lung Cancer

Summary Report

About: Clinical benefit analysis in lung cancer precision medicine.

Findings: The report summarized how precision-based approaches may contribute additional clinical insight.

lung cancer clinical benefit precision medicine
Clinical Summary
2021

Impact of Precision Medicine on Clinical Outcomes

Summary Report

About: Evaluation of how precision medicine may influence oncology outcomes.

Findings: The report outlined observed outcome patterns associated with biologically informed care planning.

clinical outcomes precision medicine summary report
This section provides a visual summary of selected publications, institutional programs, clinical studies, and precision oncology references related to molecular profiling, liquid biopsy, biomarker-guided therapy, and tumour-informed treatment approaches. Individual treatment decisions should always be interpreted in consultation with qualified healthcare professionals.
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