Vinblastine is a chemotherapy medication commonly used in the treatment of Hodgkin lymphoma, testicular cancer, and certain other malignancies. It is often administered as part of combination chemotherapy regimens.

It belongs to a class of drugs known as vinca alkaloids, which are derived from the periwinkle plant and are widely used in cancer treatment.

Vinblastine works by interfering with the formation of microtubules inside cancer cells. These structures are essential for cell division, and by disrupting them, vinblastine may prevent cancer cells from successfully dividing and multiplying.

Because it affects rapidly dividing cells, vinblastine may also impact normal tissues such as the bone marrow and digestive lining. This may lead to side effects including low blood cell counts, fatigue, and gastrointestinal symptoms.