What Is C-Statin?

C-Statin is a natural bioactive extract derived from the plant Bindweed (Convolvulus arvensis), standardized for its proteoglycan mixture (PGM) known for potent anti-angiogenic and immune-modulating properties. Unlike pharmaceutical statins that act on cholesterol pathways, C-Statin works by inhibiting abnormal blood vessel formation (angiogenesis)—a process critical for maintaining healthy tissue growth and preventing uncontrolled cellular proliferation.

Developed through advanced extraction and purification techniques, C-Statin represents a botanical innovation in cellular and vascular health, frequently utilized in integrative and adjunctive oncology and metabolic regulation protocols.

How It Works

C-Statin functions through selective modulation of angiogenic and cellular signaling pathways, helping to normalize microvascular dynamics and cellular metabolism. Its bioactive proteoglycans interact with endothelial growth factors and signaling molecules that govern capillary formation and cellular communication.

At the cellular level, C-Statin has been shown to:

• Inhibit abnormal angiogenesis, by downregulating vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF) activity

• Normalize tissue oxygenation and nutrient balance, reducing the hypoxic environment that fuels abnormal cell growth

• Support immune modulation, enhancing macrophage and lymphocyte coordination for more efficient immune surveillance

• Reduce inflammation, through suppression of NF-κB and oxidative stress signaling

• Promote apoptosis (natural cell turnover) and stabilize cellular communication pathways involved in growth regulation

Health Benefits

Extensive in vitro and clinical observations suggest that C-Statin may contribute to:

• Healthy angiogenesis balance, supporting normal tissue repair while suppressing abnormal vascular proliferation

• Immune resilience, by strengthening cellular recognition and immune response

• Cellular protection and detoxification, through regulation of oxidative and inflammatory stress

• Adjunctive oncology support, as part of integrative protocols targeting the vascular supply of abnormal cell clusters

• Metabolic and tissue balance, by optimizing nutrient distribution and energy utilization at the cellular level

• Healthy aging, through its influence on oxidative stability and vascular integrity

C-Statin’s unique selectivity allows it to target pathological angiogenesis without disrupting normal healing or tissue regeneration—an essential distinction for safe, long-term physiological support.

Sources and Supplementation

C-Statin is derived from the aerial parts of Convolvulus arvensis using proprietary extraction methods to isolate and concentrate its proteoglycan complex (PGM).
It is available as a standardized dietary supplement, commonly in capsule or liquid extract form, ensuring controlled potency and consistency.

For enhanced efficacy, C-Statin is often formulated with synergistic compounds such as:

• Artesunate or Artemisinin derivatives, for complementary oxidative and angiogenic modulation

• Curcumin and resveratrol, for anti-inflammatory and antioxidant reinforcement

• Vitamin C and glutathione, to support vascular repair and redox balance

Summary

C-Statin represents a breakthrough in plant-based angiogenesis regulation—bridging natural bioactivity with molecular precision.

By targeting the underlying vascular mechanisms that sustain abnormal cellular growth, C-Statin supports the body’s natural balance between repair and restraint, enabling a healthier internal environment for recovery and regeneration.

Through its selective anti-angiogenic, immune-modulating, and antioxidant effects, C-Statin has earned its place as a cornerstone in integrative cellular health strategies.
It exemplifies the principle of “targeted natural intelligence”—harnessing botanical molecules to guide the body’s own systems toward balance, resilience, and long-term vitality.